Primary axillary radiotherapy as axillary treatment in breast-conserving therapy for patients with breast carcinoma and clinically negative axillary lymph nodes

✍ Scribed by Frank J. P. Hoebers; Jacques H. Borger; Augustinus A. M. Hart; Johannes L. Peterse; Emiel J. Th. Rutgers; Joos V. Lebesque

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 100 KB
• Volume: 88
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/(sici)1097-0142(20000401)88:7<1633::aid-cncr18>3.0.co;2-s

✦ Synopsis

The objective of the current study was to evaluate the effectiveness and morbidity of primary axillary radiotherapy in breast-conserving therapy for postmenopausal, clinically axillary lymph node negative patients with early stage breast carcinoma. Between 1983-1997, 105 patients with clinically negative axillary lymph nodes and breast carcinoma were treated with wide local excision followed by radiotherapy to the breast, and axillary and supraclavicular lymph node areas.

METHODS.

Adjuvant treatment with tamoxifen was given to 75 patients. The median follow-up of patients still alive was 41 months (range, 8 -137 months). Fifty-five patients with no evidence of disease at last follow-up were examined prospectively with respect to late functional damage.