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Primary Amine-Thioureas based on tert-Butyl Esters of Natural Amino Acids as Organocatalysts for the Michael Reaction

✍ Scribed by Christoforos G. Kokotos; George Kokotos


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
219 KB
Volume
351
Category
Article
ISSN
1615-4150

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## Abstract The primary amine–thiourea based on di‐__tert__‐butyl (__S__)‐aspartate and (1__R__,2__R__)‐1,2‐diphenylethylene‐1,2‐diamine has been successfully employed in the “difficult” Michael reaction between aromatic ketones or acetone with nitrodienes. The high stability and reactivity of the