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Preventive treatment of rabbit coccidiosis with α-difluoromethylornithine

✍ Scribed by B.V. San Martin-Nuñez; D. Ordoñez-Escudero; J.M. Alunda


Book ID
103686173
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
501 KB
Volume
30
Category
Article
ISSN
0304-4017

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Difluoromethylornithine (DFMO) is an irreversible enzyme-activated inhibitor of ornithine decarboxylase, a key enzyme in polyamine synthesis. We have screened for potential anti-cancer activity of DFMO using a clonogenic assay, which suggested that melanoma might have sensitivity to this agent. Acco