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Preventive gastrectomy in patients with gastric cancer risk due to genetic alterations of the E-cadherin gene defect

✍ Scribed by A. Schwarz


Publisher
Springer
Year
2003
Tongue
English
Weight
143 KB
Volume
388
Category
Article
ISSN
1435-2451

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## Abstract The genetic polymorphisms in E‐cadherin gene (__CDH1__) may affect invasive/metastatic disease development by altering gene transcriptional activity. In this paper, we investigated the effect of 3′‐UTR +54C/T polymorphism (rs1801026) in __CDH1__ gene on the risk and progression of sever