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Preventive effect of Metformin against N-nitrosodiethylamine-initiated hepatocellular carcinoma in rats

โœ Scribed by Muhammad Afzal; Imran Kazmi; Gaurav Gupta; Mahfoozur Rahman; Vishwadeepak Kimothi; Firoz Anwar


Book ID
118481280
Publisher
Elsevier
Year
2012
Tongue
English
Weight
596 KB
Volume
20
Category
Article
ISSN
1319-0164

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Alterations of the Fhit gene in hepatoce
โœ Toshifumi Tsujiuchi; Yasutaka Sasaki; Tadahiko Kubozoe; Masahiro Tsutsumi; Yoich ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 115 KB

The present study was conducted to assess whether Fhit gene alterations are a feature of hepatocellular carcinomas (HCCs) induced by N-nitrosodiethylamine (DEN) in male Fischer 344 rats. Animals, 6 wk old, received a single intraperitoneal injection of DEN at a dose of 10 mg/kg body weight, followed