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Preventive effect of Chyavanprash against steroid induced cataract in the developing chick embryo

✍ Scribed by T. Velpandian; P. Mathur; S. Sengupta; S. K. Gupta

Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
188 KB
Volume
12
Category
Article
ISSN
0951-418X

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✦ Synopsis

The anticataract potential of Chyavanprash, a popular herbal formulation of India was investigated in hydrocortisone-induced cataract in the developing chick embryo. Aqueous extracts of Chyavanprash (3% and 10%) were applied at 3, 10 and 20 h after hydrocortisone administration. The incidence of advanced opacity (stage 4 and 5) was 33% after treatment with 3% extract, and 16.5% after treatment with 10% extract, compared with 96.6% in the control group. The aqueous extracts (3% and 10%) significantly prevented depletion of glutathione. Levels were 1.8 AE 0.22 and 1.96 AE 0.33 mmol/g wet weight of lens, respectively compared with 1.06 AE 0.073 in the control group. In conclusion Chyavanprash, which is widely used in India as an anti-aging formula, provides significant protection against HC-induced cataract in the developing chick embryo.

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