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Prevention versus chemophobia: a defence of rodent carcinogenicity tests

โœ Scribed by Infante, P.J.


Book ID
122664697
Publisher
The Lancet
Year
1991
Tongue
English
Weight
468 KB
Volume
337
Category
Article
ISSN
0140-6736

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The primary purpose of this study is to investigate the degree to which we can improve the prediction of rodent carcinogenicity (CA) by combining results from an in vitro and two in vivo genotoxicity tests. We used the Ames Salmonella assay (SAL) for the in vitro test and the micronucleus assay (MNC