✦ LIBER ✦

Prevention of tumor spread by matrix metalloproteinase-9 inhibition: old drugs, new concept

✍ Scribed by Shaul Lev; Boris Gilburd; Niza Lahat; Yehuda Shoenfeld

Book ID: 117644200
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 90 KB
Volume: 13
Category: Article
ISSN: 0953-6205
DOI: 10.1016/s0953-6205(02)00011-0

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Arsenic trioxide prevents radiation-enha

Arsenic trioxide prevents radiation-enhanced tumor invasiveness and inhibits matrix metalloproteinase-9 through downregulation of nuclear factor κB

✍ Wei, Lin-Hung; Lai, Kuo-Pao; Chen, Chi-An; Cheng, Chia-Hsien; Huang, Yun-Ju; Cho 📂 Article 📅 2004 🏛 Nature Publishing Group 🌐 English ⚖ 296 KB

2-Deoxy-L-ribose inhibits the invasion o

2-Deoxy-L-ribose inhibits the invasion of thymidine phosphorylase-overexpressing tumors by suppressing matrix metalloproteinase-9

✍ Yuichi Nakajima; Misako Haraguchi; Tatsuhiko Furukawa; Masatatsu Yamamoto; Hayao 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 762 KB

## Abstract Thymidine phosphorylase (TP), an enzyme involved in pyrimidine metabolism, is identical with an angiogenic factor, platelet‐derived endothelial cell growth factor. 2‐Deoxy‐D‐ribose (D‐dRib), the degradation product of thymidine generated by TP activity, has been suggested to be a downst

Induction of tumour cell apoptosis by ma

Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug

✍ Mitsiades, Nicholas; Anderson, Kenneth C; Poulaki, Vassiliki; Mitsiades, Constan 📂 Article 📅 2001 🏛 Informa plc 🌐 English ⚖ 185 KB

Activation of phosphatidylinositol 3-kin

Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-α-induced upregulation of matrix metalloproteinase-9: Its direct inhibition by quercetin

✍ Mun Kyung Hwang; Nu Ry Song; Nam Joo Kang; Ki Won Lee; Hyong Joo Lee 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 848 KB

Suppression of EGF-induced tumor cell mi

Suppression of EGF-induced tumor cell migration and matrix metalloproteinase-9 expression by capsaicin via the inhibition of EGFR-mediated FAK/Akt, PKC/Raf/ERK, p38 MAPK, and AP-1 signaling

✍ Yong Pil Hwang; Hyo Jeong Yun; Jae Ho Choi; Eun Hee Han; Hyung Gyun Kim; Gye Yon 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 395 KB

## Abstract **Scope:** Capsaicin is a cancer‐suppressing agent. The aim of our study was to determine the effect of capsaicin on tumor invasion and migration; the possible mechanisms involved in this inhibition were investigated in human fibrosarcoma cells. **Methods and results:** We employed inv

Suppression of phorbol-12-myristate-13-a

Suppression of phorbol-12-myristate-13-acetate-induced tumor cell invasion by bergamottin via the inhibition of protein kinase Cδ/p38 mitogen-activated protein kinase and JNK/nuclear factor-κB-dependent matrix metalloproteinase-9 expression

✍ Yong Pil Hwang; Hyo Jeong Yun; Jae Ho Choi; Keon Wook Kang; Hye Gwang Jeong 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 490 KB

Matrix metalloproteinase (MMP) plays an important role in the invasion and metastasis of cancer cells. The inhibitory effects of bergamottin, a cytochrome P450 inhibitor from Citrus paradis (grapefruit), on tumor invasion and migration and the possible mechanisms involved in this inhibition were inv