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Prevention of spontaneous neu-expressing mammary tumor development in mice transgenic for rat proto-neu by DNA vaccination

✍ Scribed by Pupa, S M; Invernizzi, A M; Forti, S; Carlo, E Di; Musiani, P; Nanni, P; Lollini, P L; Meazza, R; Ferrini, S; Menard, S


Book ID
110038844
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
217 KB
Volume
8
Category
Article
ISSN
0969-7128

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Inhibitory effect of the peptide epitalo
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Female FVB/N HER-2/neu transgenic mice from the age of 2 months were subcutaneously injected with saline, the peptide Epitalon(R) (Ala-Glu-Asp-Gly) or with the peptide Vilon(R) (Lys-Glu) in a single dose of 1 microg/mouse for 5 consecutive days every month. Epitalon treatment reduced the cumulative