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Prevention of severe toxic liver injury and oxidative stress in MCP-1-deficient mice

✍ Scribed by Elena Zamara; Sara Galastri; Sara Aleffi; Ilaria Petrai; Manuela Aragno; Raffaella Mastrocola; Erica Novo; Cristiana Bertolani; Stefano Milani; Francesco Vizzutti; Alessandro Vercelli; Massimo Pinzani; Giacomo Laffi; Giorgio LaVilla; Maurizio Parola; Fabio Marra

Book ID
116651213
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
851 KB
Volume
46
Category
Article
ISSN
0168-8278

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✍ Satoshi Ochiai; Toshiyuki Mizuno; Masataka Deie; Kazuhiko Igarashi; Yoshiki Hama πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 English βš– 149 KB

## Abstract Bach 1 is a transcription factor that negatively regulates the transcription of heme oxygenase‐1 (HO‐1), a stress‐responding protein. In this study, we investigated the reaction to oxidative stress in the meniscus of Bach 1 deficient mice, and the suppression of meniscal degeneration by