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Prevention of peripheral nerve dysfunction by an aldose reductase inhibitor in streptozotocin-diabetic rats

✍ Scribed by Ryuichi Kikkawa; Ikuo Hatanaka; Hitoshi Yasuda; Nobuyuki Kobayashi; Yukio Shigeta


Book ID
118948789
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
379 KB
Volume
33
Category
Article
ISSN
1532-8600

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✍ J. H. Mayer; D. R. Tomlinson πŸ“‚ Article πŸ“… 1983 πŸ› Springer 🌐 English βš– 759 KB

The effects of orally-administered myo-inositol have been compared with those of an aldose reductase inhibitor on acute neurological defects in experimentally diabetic rats. Three groups of streptozotocin-treated diabetic rats (50 mg/kg, IP) together with three groups of age-matched controls (saline