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Prevention of paclitaxel and cisplatin induced ovarian damage in rats by a gonadotropin-releasing hormone agonist

✍ Scribed by Bulent Ozcelik; Cagdas Turkyilmaz; Mahmut Tuncay Ozgun; Ibrahim Serdar Serin; Cem Batukan; Saim Ozdamar; Ahmet Ozturk

Book ID: 116475022
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 185 KB
Volume: 93
Category: Article
ISSN: 1556-5653
DOI: 10.1016/j.fertnstert.2009.02.054

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## Abstract Apoptosis is the biological process by which follicular cells are eliminated in atretic follicles. The aim of the present study was to examine the in vitro effect of a GnRH‐a (leuprolide acetate, LA) and its interactions with FSH, dibutyryl cAMP, and growth factors (IGF‐I, EGF, and FGF)