Natural and iatrogenic variation in hepa
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S. L. Ngui; R. Hallet; C. G. Teo
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Article
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1999
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John Wiley and Sons
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English
โ 420 KB
๐ 1 views
The existence of HBV as quasispecies is thought to be favoured by the infidelity of HBV RT, which would account for the emergence of the many natural mutants with point substitutions. RT infidelity may also underlie the hypermutation phenomenon. Indeed, the oft-reported point mutation in the preC ge