Prevention of head and neck cancer
β Scribed by Terry A. Day; Angela Chi; Brad Neville; James R. Hebert
- Book ID
- 107546379
- Publisher
- Current Science Inc.
- Year
- 2005
- Tongue
- English
- Weight
- 462 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1523-3790
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Despite significant improvements in therapeutic protocols, head and neck squamous cell carcinoma (HNSCC) remains a major health problem worldwide. The 5βyear postβtherapeutic survival rate is among the lowest of the major cancers with locoβregional relapse being the main cause of death.
## Abstract Cyclooxygenaseβ2 (COXβ2), an enzyme that catalyzes the synthesis of prostaglandins, is overexpressed in a variety of premalignant and malignant conditions, including oral leukoplakia and squamous cell carcinoma of the head and neck. Increased levels of COXβ2 may contribute to carcinogen