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Prevention of graft-versus-host disease by intrabone marrow injection of donor T cells: involvement of bone marrow stromal cells

โœ Scribed by T. Miyake; M. Inaba; J. Fukui; Y. Ueda; N. Hosaka; Y. Kamiyama; S. Ikehara


Book ID
108699798
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
327 KB
Volume
152
Category
Article
ISSN
0009-9104

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Selective depletion of marrow-T cytotoxi
โœ D. Maraninchi; C. Mawas; D. Guyotat; J. Reiffers; J. P. Vernant; N. Gratecos; J. ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 418 KB

In vitro depletion of mature pan-T lymphocytes has been widely and successfully used to prevent acute graft-versus-host disease (GVHD) after allogeneic bone-marrow transplantation (BMT). However, this procedure has been associated with a high incidence of graft failure and leukemic relapse. In this