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Prevention of experimental autoimmune uveoretinitis by blockade of osteopontin with small interfering RNA

✍ Scribed by Daiju Iwata; Mizuki Kitamura; Nobuyoshi Kitaichi; Yoshinari Saito; Shigeyuki Kon; Kenichi Namba; Junko Morimoto; Akiko Ebihara; Hirokuni Kitamei; Kazuhiko Yoshida; Susumu Ishida; Shigeaki Ohno; Toshimitsu Uede; Kazunori Onoé; Kazuya Iwabuchi

Book ID
116456999
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
856 KB
Volume
90
Category
Article
ISSN
0014-4835

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✍ Hidetoshi Yokoi; Kazunori Kato; Takeshi Kezuka; Jun-Ichi Sakai; Masahiko Usui; H 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 834 KB

Experimental autoimmune uveoretinitis (EAU) induced by immunization with interphotoreceptor retinoid-binding protein (IRBP), a retinal self antigen, has been regarded to be a typical T helper type 1 (Th1)-mediated inflammatory disease. In this study, we examined the effect of a neutralizing monoclon