Prevention of ERK activation involves melatonin-induced G1 and G2/M phase arrest in the human osteoblastic cell line hFOB 1.19
β Scribed by Lifeng Liu; Yue Zhu; Ying Xu; Russel J. Reiter
- Book ID
- 111264943
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 594 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0742-3098
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Lithium, a therapeutic agent for bipolar disorder, can induce G2/M arrest in various cells, but the mechanism is unclear. In this article, we demonstrated that lithium arrested hepatocellular carcinoma cell SMMCβ7721 at G2/M checkpoint by inducing the phosphorylation of cdc2 (Tyrβ15). T
## Abstract In this study, we first demonstrated that loratadine (LOR), a promising world widely used oral antiβhistamine, effectively inhibits growth of tumors derived from human colon cancer cells (COLO 205) in an in vivo setting. In vitro study demonstrated that the antiβtumor effects of LOR in
To determine whether overexpression of the human MnSOD transgene protected 32D cl 3 hematopoietic progenitor cells from ionizing irradiation, 32D cl 3 cells were co-electroporated with the pRK5 plasmid containing the human MnSOD transgene and SV2-neo plasmid with G418-resistant colonies selected. Tw