๐”– Bobbio Scriptorium
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Prevention of diabetes in the NOD mouse: implications for therapeutic intervention in human disease

โœ Scribed by Mark A. Bowman; Edward H. Leiter; Mark A. Atkinson


Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
804 KB
Volume
15
Category
Article
ISSN
0167-5699

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The development of diabetes in non-obese diabetic (NOD) mice, which normally takes between 3 and 7 months, can be accelerated by cyclophosphamide (CY) injections, with rapid progression to diabetes within only 2ยฑ3 weeks. This insulin-dependent diabetes mellitus (IDDM) can be prevented or delayed in