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Prevention of dementia in randomised double-blind placebo-controlled Systolic Hypertension in Europe (Syst-Eur) trial

✍ Scribed by Françoise Forette; Marie-Laure Seux; Jan A Staessen; Lutgarde Thijs; Willem H Birkenhäger; Marija-Ruta Babarskiene; Speranta Babeanu; Alfredo Bossini; Blas Gil-Extremera; Xavier Girerd; Tovio Laks; Emil Lilov; Valentine Moisseyev; Jaakko Tuomilehto; Hannu Vanhanen; John Webster; Yair Yodfat; Robert Fagard

Book ID
117311245
Publisher
The Lancet
Year
1998
Tongue
English
Weight
87 KB
Volume
352
Category
Article
ISSN
0140-6736

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## Abstract ## Background Disturbance of sleep is common in individuals with dementia where there may be reversal of the sleep‐wake cycle. People with dementia of the Alzheimer's type have melatonin secretion rhythm disorders. There is some evidence that treatment with exogenous melatonin is an ef