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Prevention of cycloheximide-induced apoptosis in hepatocytes by adenosine and by caspase inhibitors

โœ Scribed by W.Marty Blom; Hans J.G.M de Bont; Irma Meijerman; Gerard J Mulder; J.Fred Nagelkerke


Book ID
113994599
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
353 KB
Volume
58
Category
Article
ISSN
0006-2952

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Ceramide induces caspase-independent apo
โœ Brett E. Jones; Chau R. Lo; Anu Srinivasan; Karen L. Valentino; Mark J. Czaja ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 257 KB

Ceramide has been implicated as a second messenger in intracellular signaling pathways leading to apoptosis in nonhepatic cells. To determine whether ceramide can mediate hepatocyte apoptosis, the cytotoxicity of ceramide was determined in rat hepatocytes. The rat hepatocyte cell line, RALA255-10G,