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Prevention of cardiac allograft arteriosclerosis by protein-tyrosine kinase inhibitor selective for platelet-derived growth factor receptor

✍ Scribed by P Koskinen; R Sihvola; M Myllärniemi; P Häyry; E Buchdunger; K Lemström


Book ID
117237280
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
52 KB
Volume
31
Category
Article
ISSN
0041-1345

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Nitrostyrene Derivatives of Adenosine 5′
✍ Stefan Peterli; Regina Stumpf; Marc Schweizer; Urs Séquin; Helmut Mett; Peter Tr 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 German ⚖ 751 KB

## Abstract The syntheses and biological activities of some nitrostyrene derivatives of adenosine 5′‐glutarates, a novel class of selective, bi‐substrate‐type inhibitors of the EGF receptor protein tyrosine kinase with __IC__~50~ values around 1 μM. Only marginal inhibition of the tyrosine kinases