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Prevention of brain xenograft rejection by combination therapy of cyclosporin A, prednisolone and azathioprine

โœ Scribed by E.B. Pedersen; F.R. Poulsen; J. Zimmer; B. Finsen


Book ID
119109115
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
160 KB
Volume
54
Category
Article
ISSN
0165-5728

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Louvain (LOU) rats were administered either methotrexate (MTX; 0.3 mg/kg/week or 0.8 mg/kg/week intraperitoneally), cyclosporin A (CSA; 4 mg/kg/day or 10 mg/kg/day continuous infusion via osmotic pump), or a combination of both agents. The rats were immunized with native type I1 collagen (CII) to de