✦ LIBER ✦

Prevention of angiogenesis by naked DNA IL-12 gene transfer: angioprevention by immunogene therapy

✍ Scribed by Morini, M; Albini, A; Lorusso, G; Moelling, K; Lu, B; Cilli, M; Ferrini, S; Noonan, D M

Book ID: 110039470
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 264 KB
Volume: 11
Category: Article
ISSN: 0969-7128
DOI: 10.1038/sj.gt.3302175

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Systemic production of IL-12 by naked DN

Systemic production of IL-12 by naked DNA mediated gene transfer: toxicity and attenuation of transgene expression in vivo

✍ Vivian Wai Yan Lui; Louis Domenic Falo Jr; Leaf Huang 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 159 KB

Background IL-12 is a potent antitumor cytokine for cancer gene therapy. Previously, we demonstrated that single systemic administration of naked DNA (encoding IL-12) could serve as a good model for in vivo evaluation of the antitumor effect of a candidate gene (unpublished data). In the present stu

Gene therapy for streptozotocin-induced

Gene therapy for streptozotocin-induced diabetic mice by electroporational transfer of naked human insulin precursor DNA into skeletal muscle in vivo

✍ Dong Yin; Jian-Guo Tang 📂 Article 📅 2001 🏛 Elsevier Science 🌐 English ⚖ 120 KB

NK and CD8+ T cell-mediated eradication

NK and CD8+ T cell-mediated eradication of poorly immunogenic B16-F10 melanoma by the combined action of IL-12 gene therapy and 4-1BB costimulation

✍ Dongping Xu; Peidi Gu; Ping-Ying Pan; Qingsheng Li; Alice I. Sato; Shu-Hsia Chen 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 French ⚖ 151 KB

## Abstract In previous reports, systemic administration of a stimulatory monoclonal antibody directed against the 4‐1BB receptor had no effect on survival or tumor burden in mice inoculated with the poorly immunogenic B16‐F10 melanoma. We combined IL‐12 gene transfer with 4‐1BB costimulation to ex