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Prevalence of TT virus infection in blood donors with elevated ALT in the absence of known hepatitis markers

✍ Scribed by Peter J Cleavinger; David H Persing; Haijing Li; S.Breanndan Moore; Michael R Charlton; Corey Sievers; Terry M Therneau; Nizar N Zein


Book ID
119396994
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
138 KB
Volume
95
Category
Article
ISSN
0002-9270

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A recent report has described the molecular cloning and characterization of a novel, single-stranded DNA virus, named TT virus (TTV), which was present in the sera of Japanese patients with posttransfusion hepatitis of unknown etiology [Okamoto et al. (1998) Hepatology Research 10:1-16]. Using a nes

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## Abstract Serum samples from 1,765 consecutive Sardinian blood donors, negative for hepatitis B surface antigen (HBsAg) and for antibodies to human immunodeficiency virus (HIV) (anti‐HIV), were evaluated for the presence of antibodies to hepatitis C virus (anti‐HCV) by second‐generation ELISA. An