Prevalence of reactivation of hepatitis B virus replication in rheumatoid arthritis patients
β Scribed by Yukitomo Urata; Ryoko Uesato; Dai Tanaka; Kenji Kowatari; Taisuke Nitobe; Yoshihide Nakamura; Shigeru Motomura
- Book ID
- 106292319
- Publisher
- Springer
- Year
- 2010
- Tongue
- English
- Weight
- 172 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1439-7595
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## BACKGROUND. A point mutation from G to A at nucleotide (nt) 1896 of the precore region of hepatitis B virus (HBV) DNA has been shown to be associated with fulminant and severe hepatitis. Further studies have suggested that this point mutation, together with additional mutations in the precore p
The purposes of this study were (a) to describe the clinical and biochemical manifestations associated with spontaneous reactivation of hepatitis B virus as defined by the reappearance of hepatitis B virus DNA in serum using dot-blot hybridization and (b) to determine whether the clinical and bioche