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Prevalence of maternally inherited diabetes and deafness in Australian diabetic subjects


Book ID
113017944
Publisher
Springer
Year
1999
Tongue
English
Weight
73 KB
Volume
42
Category
Article
ISSN
0012-186X

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Maternally inherited diabetes and deafne
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## Maternally inherited diabetes and deafness (MIDD) is a new sub-type of diabetes and results from an A to G substitution at position 3243 of the mitochondrial tRNA Leu(UUR) gene. This mutation is also associated with a neurological syndrome (MELAS). Recent studies have screened carefully select

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Two types of retinopathy, diabetic and pigmentary, may be seen in subjects with maternal inheritance diabetes and deafness. The potential for interactions between the two retinopathies has not been explored. The mitochondrial mutation may affect development of diabetic retinopathy in subjects with M