The prevalence of human T-cell leukaemia virus-I and -II infection was studied in a cohort of 346 intravenous and nonintravenous drug users in Amsterdam. Three participants (0.86%) had antibodies to HTLV-I by two commercially available HTLV-I enzyme immunoassays (EIA). Infection in these three subje
Prevalence of human T-cell leukemia virus antibody among heterosexuals living in Amsterdam, the Netherlands
✍ Scribed by G. J. J. van Doornum; C. Hooykaas; J. G. Huisman; M. M. D. van der Linden; R. A. Coutinho
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 630 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0146-6615
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✦ Synopsis
Abstract
To determine the heterosexual spread of human T‐cell leukemia virus (HTLV‐I) infections, a cohort of 472 individuals with more than 5 heterosexual partners in the 6 months before entry was studied. They were recuited from visitors to the Clinic for Sexually Transmitted Diseases of the Municipal Health Service. Half of the study group was born in the Netherlands, 13% in Surinam or the Dutch Antilles, and 8% in Turkey or Morocco. Seventy percent were involved in commercial sex.
Three persons were positive for HTLV‐I, with serum antibodies against p19, p24, p28, gp46, and gp61 in Western immunoblot (WIB) and radio‐immunoprecipitation assay (RIPA). Two of them originated from Surinam and the third was a Dutch woman. Two other individuals were HIV‐positive, 19% had hepatitis B virus (HBV)‐markers and 6% Treponema pallidum reacted in the hemagglutination assay (TPHA). It is concluded that HTLV‐I ciruclates in the Surinamese population in Amsterdam and there was no evidence of appreciable heterosexual transmission.
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