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Prevalence of antibody to delta antigen among HBV carriers in Japan

✍ Scribed by Ikuo Tamura; Hiroshi Ichimura; Yoshiharu Itoh; Osamu Kurimura; Takashi Kurimura

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
262 KB
Volume
22
Category
Article
ISSN
0146-6615

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✦ Synopsis

Of 280 hepatitis B virus (HBV) carriers in Kure, Hiroshima Prefecture, Japan, 14 (5.0%) were seropositive for antibody to delta antigen (anti-HD by radioimmunoassay. HBV carriers with chronic liver disease had a greater frequency of seropositivity of anti-HD than asymptomatic HBV carriers (7% vs. 0%, P less than 0.05). Among the various geographic regions of Kure, the east suburban area had a significantly higher prevalence of anti-HD when compared with all other regions combined (9.8% vs. 2.7%, P less than 0.025). It is suggested that hepatitis delta virus (HDV) infection exists in Japan and HDV may be an etiologic agent of chronic liver disease.

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