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Prevalence of antibodies to human T-lymphotropic virus-III (HTLV-III) in hemopheliacs and other patients chronically substituted with blood products

✍ Scribed by Erfle, V. ;Hehlmann, R. ;Mellert, W. ;Goebel, F. D. ;Rasokat, H. ;Lechler, E. ;Hellstern, P. ;K�hler, M. ;Seifried, E. ;Heimpel, H.

Publisher: Springer-Verlag
Year: 1985
Weight: 493 KB
Volume: 51
Category: Article
ISSN: 1432-0584
DOI: 10.1007/bf00320518

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✦ Synopsis

The prevalence of antibodies to human T-lymphotropic virus III (HTLV-III) was determined in a total of 140 hemophiliacs and 36 polytransfused patients from three medical centers by an enzyme linked immunosorbent assay (ELISA) and confirmatory tests. 58 hemophiliacs (41.4%) were seropositive. In all instances where the origin of the coagulation factors given to these patients could be determined, blood products came from the United States. In addition, 2 of 36 polytransfused patients, mostly with acute leukemias, who were transfused with blood products from local donors were positive for HTLV-III antibodies. No HTLV-III antibodies were detected in 237 blood donors selected in part from the donor pool of the polytransfused patients.

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