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Prevalence of a non-A, non-B-associated antigen/antibody system detected by radioimmunoassay in acute and chronic liver disease

✍ Scribed by Kang-Xian Luo; Peter Karayiannis; David Macdonald Burns; May Bamber; Peter Kernoff; Dr Howard Thomas

Publisher: John Wiley and Sons
Year: 1983
Tongue: English
Weight: 532 KB
Volume: 12
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890120405

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✦ Synopsis

An antigen/antibody system associated with one form of parenterally transmitted non-A, non-B (NANB) hepatitis has been identified by solid-phase radioimmunoassay (RIA). The antigen is found in 3% of normal subjects and in increased frequency in patients with haemophilia, renal homograft recipients, homosexual men, prostitutes, drug addicts, and patients with chronic hepatitis B virus (HBV) infection. The antigen was found in normal frequency in patients with acute hepatitis A and B, sporadic NANB hepatitis (nondrug addicts), autoimmune and alcohol-induced chronic liver disease, and primary biliary cirrhosis.

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