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Prevalence and predictive value of anti-cyclic citrullinated protein antibodies for future development of rheumatoid arthritis in early undifferentiated arthritis

✍ Scribed by Yasser Emad; Mohamed Shehata; Yasser Ragab; Ahmed Saad; Hosny Hamza; Alaa Abou-Zeid

Publisher: Springer
Year: 2010
Tongue: English
Weight: 339 KB
Volume: 20
Category: Article
ISSN: 1439-7595
DOI: 10.1007/s10165-010-0286-6

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## Abstract ## Objective Anti–cyclic citrullinated peptide (anti‐CCP) antibodies are rheumatoid arthritis (RA)–specific serologic markers. RA susceptibility has been associated with HLA–DRB1 shared epitope (SE) alleles and single‐nucleotide polymorphism (SNP) haplotypes in the peptidyl arginine de