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Prevalence and genotype of hepatitis C virus infection in pregnant women and blood donors in Ghana

✍ Scribed by M.H. Wansbrough-Jonesl; E. Frimpong; B. Cant; K. Harris; M.R.W. Evans; C.G. Teo

Publisher: Elsevier Science
Year: 1998
Tongue: English
Weight: 486 KB
Volume: 92
Category: Article
ISSN: 0035-9203
DOI: 10.1016/s0035-9203(98)90887-2

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✦ Synopsis

The seroprevalence of hepatitis C virus was evaluated in blood donors and antenatal clinic attenders in Kumasi, Ghana and seropositive subjects were tested for hepatitis C virus ribonucleic acid by the polymerase chain reaction (PCR).The overall seroprevalence among Ghanaians was 2.8% but there was a significantly higher prevalence in males (4.6%) than in females (1.0%). No risk factor for infection was identified by a questionnaire. Among those who showed evidence of active infection with a positive PCR, the most common genotype was type 2 but the subtype could not be specifically determined; these type 2 hepatitis C viruses may be indigenous to Africa.

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