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Prevalence and genetic analysis of α-thalassemia and β-thalassemia in Chongqing area of China

✍ Scribed by Yao, Xiu-Yun; Yu, Jie; Chen, Shi-Ping; Xiao, Jian-Wen; Zheng, Qi-Chen; Liu, Hai-Yan; Zhang, Lei; Xian, Ying; Zou, Lin

Book ID
121894280
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
860 KB
Volume
532
Category
Article
ISSN
0378-1119

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## Abstract Thalassemias are a group of genetic hemolytic disorders with varying phenotypes. In this study, the frequency of α globin gene deletions was studied in the β‐thalassemia trait, the mildest form of the disorder. Eleven out of 33 (33%) individuals were positive for α^−3.7 kb^ deletions. N