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Prevalence and common genotypes of HCV infection in Sudanese patients with hepatosplenic schistosomiasis

✍ Scribed by H.M.Y. Mudawi; H.M. Smith; I.A. Fletcher; S.S. Fedail

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 80 KB
Volume: 79
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.20865

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

A cross‐sectional hospital based study was carried out at the National Center for Gastrointestinal and Liver Disease in Khartoum, Sudan to determine the prevalence, common genotypes and risk factors for hepatitis C virus infection in Sudanese patients with hepatosplenic schistosomiasis. A total of 176 patients with hepatosplenic schistosomiasis were tested for HCV antibodies and 4.5% of the samples were reactive. PCR was positive in 2.3% of cases and genotype 4 was the major genotype isolated with subtypes 4, 4e, and 4c/4d. It is concluded that HCV was of low seroprevalence in the study population and that parenteral antischistosomal therapy was not a significant risk factor in transmission of infection in the Sudan. J. Med. Virol. 79:1322–1324, 2007. © Wiley‐Liss, Inc.

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