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Prevalence and clinical significance of anti-C1q antibodies in cutaneous and systemic lupus erythematosus

✍ Scribed by Hegazy, Asmaa; Barakat, Amira F.; El Gayyar, Maha A.; Arafa, Lamiae F.


Book ID
119234163
Publisher
Springer (Biomed Central Ltd.)
Year
2012
Tongue
English
Weight
423 KB
Volume
13
Category
Article
ISSN
1110-8630

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Sera from patients with SLE frequently contain IgM and IgG antibodies with multiple specificities for lymphocyte surface determinants, including autologous antigens. The IgM antibodies are of relatively low binding avidity and exhibit broad reactivity with B and T lymphocytes from most individuals.