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โœฆ   LIBER   โœฆ

Pretransplant cryptococcosis and outcome after liver transplantation

โœ Scribed by Costi D. Sifri; Hsin-Yun Sun; Thomas V. Cacciarelli; Brian Wispelwey; Timothy L. Pruett; Nina Singh


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
77 KB
Volume
16
Category
Article
ISSN
1527-6465

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โœฆ Synopsis


The posttransplant outcomes and optimal management of patients with end-stage liver disease who develop cryptococcosis prior to transplantation have not been defined. We discuss these issues in the context of successful liver transplantation and pretransplant cryptococcal disease. Our report suggests that liver transplantation may be cautiously considered under the umbrella of fluconazole therapy in patients with end-stage liver disease and pretransplant cryptococcosis, provided that disease control is achieved with adequate treatment before transplantation.


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Key Points 1. Chronic kidney disease is a common complication after liver transplantation and has a major impact on graft and patient survival. 2. Pretransplant renal dysfunction is the most important determinant of posttransplant chronic kidney disease; other factors include the presence of diabete