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Presystemic bradykinin metabolism in sheep and rat nasal homogenates

✍ Scribed by Francis Y. Chung; Maureen D. Donovan

Book ID
102916651
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
598 KB
Volume
84
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES

Bradykinin metabolism in rat and sheep n
Bradykinin metabolism in rat and sheep nasal secretions
✍ Francis Y. Chung; Maureen D. Donovan πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 English βš– 674 KB

The nasal secretions are the first barrier that nasally administered drugs encounter. Therefore, the characterization of peptide metabolism in the nasal secretions is essential to predict nasal peptide bioavailability. Metabolism of bradykinin was measured in rat and sheep nasal secretions to estima

Identification and characterization of B
Identification and characterization of B2 bradykinin receptors in sheep nasal turbinate membranes
✍ R.A Lyon; P.S Weisshaar; R.J Phipps πŸ“‚ Article πŸ“… 1990 πŸ› Elsevier 🌐 English βš– 380 KB

Because bradykinin (BK) has been implicated as a mediator of upper respiratory tract symptomatology, specific 3H-BK binding was investigated in membrane homogenates prepared from sheep nasal turbinate tissue in order to identify and characterize the BK receptor subtype(s) present. 3H-BK saturation a