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Presynaptic opioid κ-receptor and regulation of the release of Met-enkephalin in the rat brainstem

✍ Scribed by Ueda, Hiroshi; Fukushima, Nobuyuki; Ge, Ming; Takagi, Hiroshi; Satoh, Masamichi


Book ID
122534023
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
272 KB
Volume
81
Category
Article
ISSN
0304-3940

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Previous studies showed that spinal opioidergic neurotransmission is markedly altered in the polyarthritic rat, a model of chronic inflammatory pain. Present investigations aimed at assessing possible changes in opioid-mediated control of the spinal outflow of met-enkephalin (ME) and dynorphin (DYN)