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Presymptomatic thyroidectomy in multiple endocrine neoplasia 2a

✍ Scribed by O. Heizmann; F.-M. Haecker; U. Zumsteg; B. Müller; M. Oberholzer; D. Oertli

Book ID
116442568
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
91 KB
Volume
32
Category
Article
ISSN
0748-7983

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Medullary thyroid carcinoma occurs sporadically or as a part of the inherited cancer syndrome multiple endocrine neoplasia (MEN) type 2. The MEN 2 gene has been identified as the RET proto-oncogene on chromosome 10. In MEN 2A, RET mutations are detectable in one of five cysteine codons within exons