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Presumptive increase in protein-bound serum calcium in a dog with multiple myeloma

✍ Scribed by Chelsea D. Tripp; Jeffrey N. Bryan; Tamara B. Wills


Book ID
118092996
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
261 KB
Volume
38
Category
Article
ISSN
0147-0701

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## Abstract Dickkopf‐1 (DKK‐1) protein, a soluble inhibitor of Wnt signalling, has been implicated in the pathogenesis of myeloma bone disease through the suppression of osteoblast differentiation. In this study, serum concentrations of DKK‐1 were measured in 50 myeloma patients (32 at diagnosis an