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Pressure-induced amorphization and disordering on cooling in a crystalline polymer

✍ Scribed by Rastogi, Sanjay; Newman, Mark; Keller, Andrew


Book ID
109778113
Publisher
Nature Publishing Group
Year
1991
Tongue
English
Weight
442 KB
Volume
353
Category
Article
ISSN
0028-0836

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The feasibility of using excipients to suppress the amorphization or structural disorder of crystalline salbutamol sulphate (SS) during milling was investigated. SS was subjected to ball-milling in the presence of a-lactose monohydrate (LAC), adipic acid (AA), magnesium stearate (MgSt), or polyvinyl