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Pressure distortion of an artificial membrane and the effect of ligand/protein binding

✍ Scribed by Richard B. Philp; Donald J.L. McIver; Patrick T.T. Wong


Book ID
115729561
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
500 KB
Volume
1021
Category
Article
ISSN
0005-2736

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Effect of ligand binding on the intramin
✍ Burak Alakent; Sena Baskan; Pemra Doruker πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 876 KB

## Abstract Effects of ligand binding on protein dynamics are studied via molecular dynamics (MD) simulations on two different enzymes, dihydrofolate reductase (DHFR) and triosephosphate isomerase (TIM), in their unliganded (free) and liganded states. Domain motions in MD trajectories are analyzed