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Preserved learning and memory following 5-fluorouracil and cyclophosphamide treatment in rats

✍ Scribed by Jeffrey M. Long; Garrick D. Lee; Bennett Kelley-Bell; Edward L. Spangler; Evelyn J. Perez; Dan L. Longo; Rafael de Cabo; Sige Zou; Peter R. Rapp

Book ID
113842290
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
420 KB
Volume
100
Category
Article
ISSN
0091-3057

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## Abstract A total of 240 outbred Sprague‐Dawley rats were treated with 3 different doses of the cyclophosphamide‐methotrexate‐5‐fluorouracil (CMF) regimen adopted from clinical chemotherapy studies in breast cancer patients. Eighty untreated rats served as controls. Individual and total doses of