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Preserved induction of long-term potentiation in the stratum radiatum in CA1 field of hippocampal slices from transgenic mice overexpressing ornithine decarboxylase and overproducing putrescine

✍ Scribed by R. Pussinen; J. Sirviö; L. Alhonen; J. Larson; M. Halmekytö; E. Koivisto; J. Jänne


Book ID
119578139
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
147 KB
Volume
5
Category
Article
ISSN
0928-4680

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Preserved induction of long-term potenti
✍ R. Pussinen; J. Sirviö; L. Alhonen; J. Larson; M. Halmekytö; E. Koivisto; J. Jän 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 55 KB 👁 2 views

The role of putrescine in synaptic neurotransmission and plasticity was studied using transgenic mice overexpressing ornithine decarboxylase (ODC), a polyamine-synthesizing enzyme. Transgenic mice were produced using the standard microinjection technique leading to elevated levels of putrescine in t