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Preservation of the substanitia nigra and locus coeruleus in a patient receiving levodopa (2 kg) plus decarboxylase inhibitor over a four-year period

✍ Scribed by Niall Quinn; David Parkes; Ivan Janota; Prof. C. D. Marsden


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
460 KB
Volume
1
Category
Article
ISSN
0885-3185

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✦ Synopsis


A 72-year-old hypertensive man developed parkinsonism and was treated with Sinemet for 4 years but then died of a bronchial carcinoma. Necropsy revealed cerebrovascular disease and amyloid an@opathy. The substantia nigra and locus coeruleus were normal on light microscopy.