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Preservation of ovarian function and reproductive ability in patients with malignant ovarian tumors

✍ Scribed by Toshihide Miyazaki; Yutaka Tomoda; Masahiro Ohta; Takeo Kano; Kazuo Mizuno; Katsumi Sakakibara

Book ID
119052988
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
654 KB
Volume
30
Category
Article
ISSN
0090-8258

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## Abstract ## BACKGROUND. Methylation‐mediated suppression of detoxification, DNA repair, and tumor suppressor genes has been implicated in cancer development and progression. Studies also have indicated that concordant methylation of multiple genes (methylator phenotypes), rather than a single g