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Preservation of neurotrophin expression in microglia that migrate into the gerbil's brain across the blood–brain barrier

✍ Scribed by Hiromi Suzuki; Fumihiro Imai; Tetsuo Kanno; Makoto Sawada


Book ID
117472096
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
236 KB
Volume
312
Category
Article
ISSN
0304-3940

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## Abstract Neurotrophins, such as brain derived neurotrophic factor (BDNF), do not cross the blood–brain barrier (BBB). Certain monoclonal antibodies (MAb) to the human insulin receptor (HIR) do cross the BBB via receptor‐mediated transport, and can act as a molecular Trojan horse to ferry across