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Present state of immunosuppressive therapy in liver transplant recipients

✍ Scribed by Russell H. Wiesner; John J. Fung


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
349 KB
Volume
17
Category
Article
ISSN
1527-6465

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✦ Synopsis


Key Points

  1. Our increasing understanding of the signaling pathways and cellular interactions in transplant immunobiology has facilitated targeted strategies using novel immunosuppressive agents. 2. The pattern of immunosuppressive drug use in the United States continues to change, and the changes include the use of antibody induction therapy and the agents used in maintenance therapy. 3. The driving forces behind the development of new immunosuppressive regimens are the long-term complications of current immunosuppressive regimens (particularly renal dysfunction and metabolic disturbances).

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