Summary data are presented on 168 D/21 and 131 G/21 translocation trisomies reported to the New York State Chromosome Registry. By combining these data with others from the literature it is estimated that about 59% of D/21 cases are the result of mutation in hte parental generation; the rest are tra
Presenile dementia associated with unbalanced Robertsonian translocation form of Down's syndrome
โ Scribed by V.P. Prasher
- Book ID
- 119066461
- Publisher
- The Lancet
- Year
- 1993
- Tongue
- English
- Weight
- 326 KB
- Volume
- 342
- Category
- Article
- ISSN
- 0140-6736
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
A boy with both Down's and Sturge-Weber's syndrome was found to have a partial trisomy 21 as a consequence of a familial translocation t(3p-;21q+) which is not reciprocal. Judging from the structure of the involved chromosomes studied by banding and photometrical techniques, the loss of relatively l
Women with Down's syndrome experience early onset of both menopause and Alzheimer's disease. This timing provides an opportunity to examine the influence of endogenous estrogen deficiency, indicated by age at menopause, on risk of Alzheimer's disease. A community-based sample of 163 postmenopausal w
Previous work has established the presence of an unbalanced chromosome abnormality [ +der( l),t( 1 ;7)(pll ;pll)] in some therapy-associated myelodysplastic disorders. Recently the EGF receptor has been found to reside at 7pll. Using a probe specific for erb B oncogene, which encodes a truncated for