𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Presence of two forms of methylated (–)-epigallocatechin-3-gallate in green tea

✍ Scribed by Amarowicz, Ryszard ;Shahidi, Fereidoon

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
117 KB
Volume
47
Category
Article
ISSN
0027-769X

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Crude catechins extract from Chinese green tea were fractionated using Sephadex LH‐20 column chromatography. The fraction containing (–)‐epigallocatechin‐3‐gallate (EGCG) was then subjected to a semipreparative high‐performance liquid chromatography (HPLC). Using a mobile phase of water : dimethyl formamide : methanol : acetic acid (157 : 49 : 2 : 1 v/v/v/v( the mixture of two methylated catechins was separated and isolated. According to mass spectrometry (MS) and nuclear magnetic resonance (^1^H‐NMR) date, these compounds were identified as (–)‐epigallocatechin‐3‐(3‐O‐methylgallate) and (–)‐epigallocatechin‐3‐(4‐O‐methylgallate).

📜 SIMILAR VOLUMES

The green tea compound, (−)-epigallocate
The green tea compound, (−)-epigallocatechin-3-gallate downregulates N-cadherin and suppresses migration of bladder carcinoma cells
✍ Kimberly M. Rieger-Christ; Robert Hanley; Christopher Lodowsky; Trisha Bernier; 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 296 KB

## Abstract Green tea has been reported as potential dietary protection against numerous cancers and has been shown to have activity in bladder tumor inhibition in different animal models. The goal of this study was to examine the effects of (−)‐epigallocatechin gallate (EGCG—the major phytochemica

The green tea polyphenol, epigallocatech
The green tea polyphenol, epigallocatechin-3-gallate, protects against the oxidative cellular and genotoxic damage of UVA radiation
✍ Simon E. Tobi; Mileka Gilbert; Nigel Paul; Trevor J. McMillan 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 127 KB 👁 1 views

## Abstract A number of biological activities have been ascribed to the major green tea polyphenol epigallocatechin‐3‐gallate (EGCG) to explain its chemopreventive properties. Its antioxidant properties emerge as a potentially important mode of action. We have examined the effect of EGCG treatment

Green tea catechin, epigallocatechin-3-g
Green tea catechin, epigallocatechin-3-gallate, inhibits vascular endothelial growth factor angiogenic signaling by disrupting the formation of a receptor complex
✍ Shaun K. Rodriguez; Weimin Guo; Liping Liu; Michael A. Band; Eric K. Paulson; Mo 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 474 KB 👁 1 views

## Abstract A potential mechanism by which green tea may prevent cancer development is through the inhibition of angiogenesis. We have shown previously that the green tea catechin, epigallocatechin gallate (EGCG), inhibits endothelial cell tube formation through the inhibition of vascular endotheli

Green tea polyphenol (–)-epigallocatechi
Green tea polyphenol (–)-epigallocatechin gallate reduces neuronal cell damage and up-regulation of MMP-9 activity in hippocampal CA1 and CA2 areas following transient global cerebral ischemia
✍ Jong-Wan Park; Young-Ho Jang; Jin-Mo Kim; Hyung Lee; Weon-Kyun Park; Man-Bin Lim 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 402 KB

## Abstract Previous studies have demonstrated that (–)‐epigallocatechin gallate (EGCG), a green tea polyphenol, protects against ischemia and reperfusion‐induced injury in many organ systems. Here, we test the hypothesis that part of EGCG's neuroprotective effects may involve a modulation of matri